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7-Azabicyclo[2.2.1]heptane N-imide as an intermediate in the thermal decomposition of N-amino-7-azabicyclo[2.2.1]heptane and the corresponding benzenesulphonamide

โœ Scribed by Dervan, Peter B.; Uyehara, Tadao


Book ID
121343049
Publisher
The Royal Society of Chemistry
Year
1976
Tongue
English
Weight
170 KB
Volume
12
Category
Article
ISSN
0022-4936

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โœ Satendra Singh; Garo P. Basmadjian ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 110 KB

heptane, an important intermediate for the synthesis of epibatidine and its analogs was efficiently synthesized from N-BOC-exo-2-(methoxycarbonyl)-7azabicyclo[2.2.1]hepta-2,5-diene (5) via hydrogenation followed by reductive dehalogenation or via hydrodehalogenation followed by epimerization. The di