𝔖 Bobbio Scriptorium
✦   LIBER   ✦

6′,7′-Dihydrokeramamine C and analogues: synthesis and biological evaluation

✍ Scribed by Annie Pouilhès; Monica Duval-Lungulescu; Stéphanie Lambel; Stéphane Léonce; Yves Langlois


Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
63 KB
Volume
42
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

✦ Synopsis


6%,7%-Dihydrokeramamine C 7d and analogues have been synthesised and evaluated for their cytotoxicity. Compound 7f in which the azacycloundecane ring has been substituted by a dihexylamino unit showed increasing biological activity.


📜 SIMILAR VOLUMES


Synthesis and Biological Evaluation of C
✍ Fei Chen; An-Hui Gao; Jia Li; Fa-Jun Nan 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 436 KB 👁 1 views

Largazole (1) is a densely functionalized macrocyclic depsipeptide that was isolated from the cyanobacterium Symploca sp.

Synthesis and Biological Evaluation of 2
✍ Mao-Chin Liu; Mei-Zhen Luo; Diane E. Mozdziesz; Alan C. Sartorelli 📂 Article 📅 2007 🏛 John Wiley and Sons ⚖ 31 KB 👁 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.

Design, synthesis and biological evaluat
✍ Amir P. Tamiz; Miles P. Smith; Alan P. Kozikowski 📂 Article 📅 2000 🏛 Elsevier Science 🌐 English ⚖ 154 KB

The synthesis and biological activity of a series of azatricyclodecane analogues of cocaine are described. All compounds studied in this series exhibit nanomolar potency and good selectivity for the serotonin transporter versus the dopamine transporter.