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618 Identification of Novel p53-regulated Genes Involved in Chromatin Remodeling in Response to DNA Damage

✍ Scribed by L. Castellini; A.J. Krieg; S.S. Mello; A.J. Giaccia


Book ID
117663105
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
54 KB
Volume
48
Category
Article
ISSN
0959-8049

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## Abstract The p53 tumor suppressor gene, which is frequently mutated in a wide variety of tumors, plays an important role in maintaining genomic integrity. Following genotoxic insults, the protein level of p53 is increased, and p53 functions as a sequence‐specific transcription factor that regula