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61 Pharmacokinetics and isolated liver perfusion of carbohydrate modified tissue-type plasminogen activator

✍ Scribed by Tanswell, P.; Schlüter, M.; Krause, J.

Book ID
123036448
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
122 KB
Volume
2
Category
Article
ISSN
0268-9499

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A recent study presented plasma concentrations of tissue-type plasminogen activator in three different animal species and at several different dose levels. A three-compartment mammillary model with capacity-limited elimination (of Michaelis -Menten form) was postulated to describe the data. In the