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Pharmacokinetic allometric scaling of coagulation factors and tissue-type plasminogen activators

✍ Scribed by I. MAHMOOD


Book ID
108775297
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
84 KB
Volume
15
Category
Article
ISSN
1351-8216

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To investigate the effect of tissue-type plasminogen activator (t-PA) on blood coagulation, we examined the effects of the addition of t-PA to normal pool plasma (NPP) on clotting times such as diluted prothrombin time (PT) and kaolin clotting time (KCT). The diluted PT but not the KCT was significa