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609 Tumor Necrosis Factor-α and Lymphotoxin-α1β2 Induce Enteric Neuronal Differentiation Through the NfκB Signaling Pathways

✍ Scribed by Rachel L. Poole; William Yen; Fang Li; Shanthi Srinivasan; Wenhui Hu


Book ID
119430301
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
81 KB
Volume
136
Category
Article
ISSN
0016-5085

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## Abstract Resistance to tumor necrosis factor (TNFα)‐induced apoptosis in various cancer cells has been attributed to the activation of the transcription factor NF‐κB. Ebselen (2‐phenyl‐1,2‐benzisoselenazol‐3[2H]one)—a selenoorganic compound is known to prevent TNFα‐mediated NF‐κB activity. As gl