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6-Hydroxydopamine-induced degeneration of nigral dopamine neurons: Differential effect on nigral and striatal D-1 dopamine receptors

โœ Scribed by M.L. Porceddu; O. Giorgi; G. De Montis; S. Mele; L. Cocco; E. Ongini; G. Biggio


Book ID
118342504
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
460 KB
Volume
41
Category
Article
ISSN
0024-3205

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โœ Elizabeth M. Byrnes; Anne Reilly; John P. Bruno ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 267 KB

The ability of locally-administered AMPA and D1 receptor ligands to modulate in vivo striatal and nigral GABA efflux was determined in awake, intact male rats using a dual-probe microdialysis technique. Intrastriatal perfusion of AMPA (100 ยตM) produced a 50-100% increase in striatal GABA efflux that