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5H-Pyrimido[4,5-b][1,4]thiazin-6(7H)-one. The Product of a Novel Cyclization Reaction 1

✍ Scribed by Piper, James R.; Johnston, Thomas P.


Book ID
120584732
Publisher
American Chemical Society
Year
1965
Tongue
English
Weight
219 KB
Volume
30
Category
Article
ISSN
0022-3263

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Synthesis of novel 6,7-dihydro-5H-pyrimi
✍ Jinbao Xiang; Xiaowei Hu; Qun Dang; Xu Bai πŸ“‚ Article πŸ“… 2011 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 84 KB

## Abstract A new method was developed for the synthesis of 6,7‐dihydro‐5__H__‐pyrimido[4,5‐__e__][1,4]diazepin‐8(9__H__)‐one derivatives. The key to construct the pyrimido[4,5‐__e__][1,4]diazepine core is the intramolecular amidation of __N__‐((4‐amino‐6‐chloropyrimidin‐5‐yl)methyl)‐substituted am