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591 Berberine sensitizes TRAIL-induced apoptosis through proteasomemediated down-regulation of c-FLIP and Mcl-1 proteins

✍ Scribed by T.J. Lee; S.J. Lee; H.J. Noh; E.G. Sung; I.H. Song; J.Y. Kim


Book ID
119603274
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
45 KB
Volume
8
Category
Article
ISSN
1359-6349

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✍ Jin Yeop Kim; Eun Hee Kim; Seok Soon Park; Jun Hee Lim; Taeg Kyu Kwon; Kyeong So 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 460 KB

## Abstract This study demonstrates that combined treatment with subtoxic doses of quercetin (3′,3′,4′,5,7‐pentahydroxyflavone), a flavonoid found in many fruits and vegetables, plus tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) induces rapid apoptosis in TRAIL‐resistant hepatocel