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5,8,11,14-Eicosatetraynoic Acid-Induced Destruction of Mitochondria in Human Prostate Cells (PC-3)

✍ Scribed by Kenning M. Anderson, Thomas M. Seed, Diana E. Wilson and Jules E. Harris


Book ID
125620749
Publisher
Society for In Vitro Biology
Year
1992
Tongue
English
Weight
712 KB
Volume
28A
Category
Article
ISSN
1475-2689

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Phospholipase D (PLD) is activated in mammalian cells in response to a variety of growth factors and may play a role in cell proliferation. Lysophosphatidic acid (LPA) is a bioactive metabolite potentially generated as a result of PLD activation. Two human prostate cancer cell lines, PC-3 and LNCaP,