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5,8,11,14-Eicosatetraynoic acid-induced destruction of mitochondria in human prostate cells (PC-3)

✍ Scribed by Kenning M. Anderson; Thomas M. Seed; Diana E. Wilson; Jules E. Harris


Book ID
112803470
Publisher
Society for In Vitro Biology
Year
1992
Tongue
English
Weight
625 KB
Volume
28
Category
Article
ISSN
1475-2689

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Phospholipase D (PLD) is activated in mammalian cells in response to a variety of growth factors and may play a role in cell proliferation. Lysophosphatidic acid (LPA) is a bioactive metabolite potentially generated as a result of PLD activation. Two human prostate cancer cell lines, PC-3 and LNCaP,