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572 Production of cytolytic T cell (CTL) clones directed against autologous small cell and non-small cell lung cancer cell lines

✍ Scribed by Weynants, P.; Marchand, M.; Baurain, J.F.; Deloos, M.; Boon, T.; Coulie, P.G.

Book ID
123440389
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
143 KB
Volume
18
Category
Article
ISSN
0169-5002

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We have attempted to optimize the production of stable human cytolytic T lymphocyte clones directed against autologous melanoma cell lines. MLTC were restimulated every week with irradiated melanoma cells in medium containing human serum and IL-2. After 21 to 35 days, in 5 out of 6 patients, these c