The androgen receptor can signal through
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Liang Schweizer; Cheryl A Rizzo; Thomas E Spires; J Suso Platero; Qiuyan Wu; Tai
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Article
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2008
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BioMed Central
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English
⚖ 816 KB
## Background A crucial event in Prostate Cancer progression is the conversion from a hormone-sensitive to a hormone-refractory disease state. Correlating with this transition, androgen receptor (AR) amplification and mutations are often observed in patients failing hormonal ablation therapies. β-C