## BACKGROUND. The purpose of this study was to determine the contribution of different transactivating regions of the androgen receptor (AR) to the induction of androgen-regulated promoters in poorly (PC3 cells) and well-differentiated (LNCaP cells) prostate cancer cell lines. METHODS. PC3 and LN
β¦ LIBER β¦
Rapid signalling by androgen receptor in prostate cancer cells
β Scribed by Peterziel, Heike; Mink, Sigrun; Schonert, Annette; Becker, Matthias; Klocker, Helmut; Cato, Andrew CB
- Book ID
- 110062418
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 391 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0950-9232
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## Abstract Since androgen receptor (AR) plays an important role in prostate cancer development and progression, androgenβablation has been the frontline therapy for treatment of advanced prostate cancer even though it is rarely curative. A curative strategy should involve functional and structural