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53 Everolimus Introduction and Calcineurin Reduction in Thoracic Transplant Recipients with Advanced Chronic Renal Failure

✍ Scribed by S. Arora; B. Rundqvist; S.-A. Mortensen; H. Eiskjær; G. Riise; L. Mared; O. Bjørtuft; B. Ekmehag; K. Jansson; S. Simonsen; E. Gude; D. Solbu; M. Iversen; L. Gullestad


Book ID
116522883
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
171 KB
Volume
30
Category
Article
ISSN
1557-3117

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Chronic renal dysfunction is a frequent and severe complication in solid-organ transplant recipients. Calcineurin inhibitors (CNIs) are the main pathogenic factors of renal dysfunction. Switching from CNIs to nonnephrotoxic drugs, such as mammalian target of rapamycin inhibitors (everolimus and siro