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Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: The significance of baseline glomerular filtration rate

✍ Scribed by Satish Arora; Einar Gude; Vilborg Sigurdardottir; Svend Aage Mortensen; Hans Eiskjær; Gerdt Riise; Lena Mared; Øystein Bjørtuft; Bjørn Ekmehag; Kjell Jansson; Svein Simonsen; Pål Aukrust; Dag Solbu; Martin Iversen; Lars Gullestad

Book ID
116523661
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
674 KB
Volume
31
Category
Article
ISSN
1557-3117

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Improvement of renal function after the
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Chronic renal dysfunction is a frequent and severe complication in solid-organ transplant recipients. Calcineurin inhibitors (CNIs) are the main pathogenic factors of renal dysfunction. Switching from CNIs to nonnephrotoxic drugs, such as mammalian target of rapamycin inhibitors (everolimus and siro