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514 POSTER Antitumor activity of aplidin® in human neuroblastoma tumors

✍ Scribed by H. Sasak; D. LePage; W. Grant; M. Elices; B. Rinehart; T. Caylor; L. Cheney; K. Halley; P. Aviles; G. Faircloth

Book ID
118624142
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
57 KB
Volume
4
Category
Article
ISSN
1359-6349

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Neuroblastoma (NB) is the most common extracranial solid tumor of childhood. In advanced disease stages, prognosis is poor and treatments have limited efficacy, thus novel strategies are warranted. The synthetic retinoid Fenretinide (HPR) induces apoptosis in NB and melanoma cell lines. We reported