The human tumor stem cell assay (HTSCA) has been used to study the in vitro sensitivity rates of anticancer drugs used in the treatment of 115 patients with previously untreated and relapsing ovarian cancer. The data from these studies have identified patterns of cross resistance and residual sensit
Antitumor activity of didemnin B in the human tumor stem cell assay
โ Scribed by T. L. Jiang; R. H. Liu; S. E. Salmon
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 392 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0344-5704
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Caspases have been implicated in the induction of apoptosis in most systems studied. The importance of caspases for apoptosis was further investigated using the system of didemnin B-induced apoptosis. We found that benzyloxycarbonyl-VAD-fluoromethylketone, a general caspase inhibitor, inhibits didem