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5-Substituted pyrimidine acyclic nucleoside analogues 1-cyanomethyl- and 1-(4-cyanobutyl)-5-substituted uracils as candidate antitumor agents

✍ Scribed by Jack C. Kim; Eun-Soo Dong; Jin Il Park; Sang-Duk Bae; Seon-Hee Kim


Book ID
112961752
Publisher
Springer
Year
1994
Tongue
English
Weight
261 KB
Volume
17
Category
Article
ISSN
0253-6269

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ChemInform Abstract: Acyclic Analogues o
✍ M. S. NOVIKOV; A. A. OZEROV πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 32 KB πŸ‘ 2 views

Acyclic Analogues of Pyrimidine Nucleosides. Synthesis of 1-(2-Hydroxyethoxy)methyl-and 1-(4-Hydroxybutyl)-5-amino Derivatives of Uracil. -Reaction of 5-aminouracil derivatives (I) with 4-bromobutyl acetate (II) or chloromethoxyethyl benzoate (V) followed by deacylation affords the title uracil der