5'-Levulinyl and 2'-tetrahydrofuranyl protection for the synthesis of oligoribonucleotides by the phosphoramidite approach
β Scribed by Iwai, Shigenori (author);Ohtsuka, Eiko (author)
- Book ID
- 121858897
- Publisher
- Oxford University Press
- Year
- 1988
- Tongue
- English
- Weight
- 713 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0305-1048
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π SIMILAR VOLUMES
For the efficient synthesis of oligoribonucleotides by the 5'-O-(4,4'-dimethoxytrityl) phosphoramidite approach, the 2'-O-[1-(benzyloxy)ethyl]acetals 56 Β± 67 were investigated. Studies with the 2'-O-[1-(benzyloxy)ethyl]-5'-O-(dimethoxytrityl)ribonucleoside 3'-phosphoramidites 56 Β± 59 gave, however,
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With best personal wishes dedicated to Prof. Dr. Albert Eschenmoser on the occassion of his 75th birthday The syntheses of the 3'-O-(4,4'-dimethoxytrityl)-protected 5'-phosphoramidites 25 Β± 28 and 5'-(hydrogen succinates) 29 Β± 32, which can be used as monomeric building blocks for the inverse (5'-3'