5-Bromodeoxyuridine induced sister chromatid exchange frequencies in primate lymphocytes
β Scribed by R. I. Barnett; J. A. Wallace
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 224 KB
- Volume
- 38
- Category
- Article
- ISSN
- 1420-682X
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## Abstract The utility of the sister chromatid exchange (SCE) assay for human population studies is potentially limited by the variability associated with individual baseline SCE frequencies. This investigation identifies and quantifies the major sources of preparative and biological variation ass
Cultured lymphocytes from 9 patients with clinically different types of xeroderma pigmentosum were exposed to ultraviolet light at 24 h. An increased rate of sister chromatid exchanges were observed in 6 patients (128--148% increase in three, 34--51% in three), but not in three patients with deSanct