Effect of deoxycytidine on frequency of sister chromatid exchanges in human lymphocytes detected with 5-bromodeoxyuridine
โ Scribed by T. L. Bairamyan
- Publisher
- Springer US
- Year
- 1978
- Tongue
- English
- Weight
- 229 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0007-4888
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๐ SIMILAR VOLUMES
The incidence of sister chromatid exchange (SCE) was determined in human lymphocytes cultured with fetal calf, human AB, and autologous serum. In each individual studied, cells grown in medium supplemented with fetal calf and human AB serum showed higher yields of SCE than those cultured with autolo
Lymphocytes from 20 notmal subjects (11 male and 9 female) were examined for the frequency and location of sister chromatid exchanges (SCE) by the BrdU--Giemsa method. The mean frequency of SCE was 6.37 with little significant variation. One subject had a high number of exchanges in chromosome 1 whi
The fluorescence-plus-Giemsa (FPG) technique for analysis of sister chromatid exchange (SCE) is widely used as an assay for mutagenic carcinogens. There is very little information, however, on whether incorporation of the bromodeoxyuridine (BrdU) necessary for visualization of SCEs affects the sensi