The relative configuration of the title compound, C~9~H~14~NO~5~, formed by catalytic hydrogenation of an azidolactone, has been established by X-ray crystallographic analysis. The absolute configuration was determined by the use of 2,3-__O__-isopropylidene-L-lyxono-1,4-lactone as the carbohydrate s
5-Amino-5-deoxy-2-C-hydroxymethyl-2,3-O-isopropylidene-d-talono-1,5-lactam
✍ Scribed by Ameijde, Jeroen van ;Cowley, Andrew R. ;Fleet, George W. J. ;Nash, Robert J. ;Simone, Michela Iezzi ;Soengas, Raquel
- Publisher
- International Union of Crystallography
- Year
- 2004
- Tongue
- English
- Weight
- 181 KB
- Volume
- 60
- Category
- Article
- ISSN
- 1600-5368
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✦ Synopsis
The title compound, C 10 H 17 NO 6 , was prepared by carrying out three S N 2 displacements on a branched sugar derivative, one of which was not planned. Its crystal structure was determined to con®rm the identity and stereochemistry of the product.
📜 SIMILAR VOLUMES
Single-crystal X-ray study T = 120 K Mean '(C±C) = 0.004 A Ê R factor = 0.045 wR factor = 0.102 Data-to-parameter ratio = 11.0 For details of how these key indicators were automatically derived from the article, see http://journals.iucr.org/e.
A second crystalline diacetonide, the title compound, C 13 H 20 O 7 , has been isolated from the sequential treatment of d-tagatose with aqueous sodium cyanide, followed by acetone in the presence of acid. Structural ambiguities with regard to the size of both the lactone and ketal rings are resolve