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4β-Isocyanopodophyllotoxins: valuable precursors for the synthesis of new podophyllotoxin analogues

✍ Scribed by Ying-Qian Liu; Lin-Hai Li; Wen-Qun Li; Gang Feng; Liu Yang

Book ID
111491498
Publisher
Versita
Year
2011
Tongue
English
Weight
151 KB
Volume
65
Category
Article
ISSN
0366-6352

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✦ Synopsis

Abstract

A new and efficient method for the synthesis of novel 4β-isocyanopodophyllotoxins as a valuable building block for the synthesis of versatile bioactive podophyllotoxin analogues under both classical and ultrasonic conditions was developed. In general, significant improvements in rates of reaction and yields of sonochemical reactions relative to the classical ones were observed.

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