✦ LIBER ✦

4(S)(6-amino-9H-purin-9-yl)tetrahydro-2(S)-furanmethanol: Synthesis, enzymology and anti-HIV studies

✍ Scribed by V. Nair; J.L. Rideout; M.H. St. Clair; H.C. Krasny; J.E. Reardon; R. Dornsife; T. Spector

Book ID: 113259209
Publisher: Elsevier Science
Year: 1995
Tongue: English
Weight: 74 KB
Volume: 26
Category: Article
ISSN: 0166-3542
DOI: 10.1016/0166-3542(95)94739-o

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Enantiomeric radiochemical synthesis of

Enantiomeric radiochemical synthesis of R and S (1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yloxy)methylphosphonic acid (FPMPA)

✍ Dale O. Kiesewetter; Kathleen Knudson; Matt Collins; Sharat Srinivasula; Esther 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 189 KB

## Abstract Therapy for human immunodeficiency virus (HIV)‐infected patients requires chronic multidrug administration. The eventual failure of therapy in some patients has brought into question the tissue concentration of the drugs. With an appropriately radiolabeled compound, we could utilize pos

ChemInform Abstract: Synthesis of Stable

ChemInform Abstract: Synthesis of Stable Solvates of Monosodium 2-((R*s,9S*)-(4-Methoxy-6,7, 8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl)sulfinyl)-1H-benzimidazole.

✍ S. YAMADA; T. GOTO; S. YUASA; T. YAMAGUCHI; K. KOGI 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 28 KB 👁 2 views

## Synthesis of Stable Solvates of Monosodium 2-((R\*s,9S\*)-(4-Methoxy-6,7, 8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl)sulfinyl)-1H-benzimidazole. -In order to improve the stability of the previously prepared novel antiulcer agent (I), 1-substituted benzimidazole derivatives are prepared, but t

Synthesis of carbon-14 labelled cis-2-am

Synthesis of carbon-14 labelled cis-2-amino-1,9-dihydro-9-[4-(hydroxy-methyl)-2-cyclopenten-1-YL]-6H-purine-6-one; [8-14C]carbovir: A promising anti-aids drug

✍ M. B. Gopinathan; J. A. Kepler 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 183 KB

The synthesis of the title compound (3) is described. Treatment of a solution of triethyl [14C]orthoformate in dry chloroform with cis-[4-(2,5-diamino-6-chloro-4-pyrimidinyl) -amino] -2cyclopentenyl]carbinol (1) afforded crude 2. Hydrolysis of crude 2 with 2 N sodium Eydroxide gave 3 in 34% overall

ChemInform Abstract: Synthesis and Antiv

ChemInform Abstract: Synthesis and Antiviral Activity of Cyclopropyl-Spirocarbocyclic Adenosine, (4R,5S,6R,7R)-4-(6-Amino-9H-purin-9-yl)-7-(hydroxymethyl)spiro [2.4]heptane-5,6-diol Against Hepatitis C Virus.

✍ Srinivas Gadthula; Ravindra K. Rawal; Ashoke Sharon; Dong Wu; Brent Korba; Chung 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 40 KB 👁 2 views

Pharmacological characterisation and inh

Pharmacological characterisation and inhibitory effects of (2R,3R,4S,5R)-2-(6-amino-2-{[(1S)-2-hydroxy-1-(phenylmethyl)ethyl]amino}-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydro-3,4-furandiol, a novel ligand that demonstrates both adenosine A2A receptor agonist and adenosine A3 receptor antagonist activity

✍ Nicola Bevan; Peter R. Butchers; Rick Cousins; Jill Coates; Emma V. Edgar; Val M 📂 Article 📅 2007 🏛 Elsevier Science 🌐 English ⚖ 241 KB

Synthesis of the Anticodon Hairpin tRNAf

Synthesis of the Anticodon Hairpin tRNAfMet Containing N-{[9-(β-D-Ribofuranosyl)-9H-purin-6-yl]carbamoyl}-L-threonine (=N6-{{[(1S,2R)-1-Carboxy-2-hydroxypropyl]amino}carbonyl}adenosine, t6A)

✍ Valerie Boudou; James Langridge; Arthur Van Aerschot; Chris Hendrix; Alan Millar 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 German ⚖ 150 KB 👁 1 views