✦ LIBER ✦

ChemInform Abstract: Synthesis of Stable Solvates of Monosodium 2-((Rs,9S)-(4-Methoxy-6,7, 8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl)sulfinyl)-1H-benzimidazole.

✍ Scribed by S. YAMADA; T. GOTO; S. YUASA; T. YAMAGUCHI; K. KOGI

Publisher: John Wiley and Sons
Year: 2010
Weight: 28 KB
Volume: 28
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199706142

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✦ Synopsis

Synthesis of Stable

Solvates of Monosodium 2-((R*s,9S*)-(4-Methoxy-6,7, 8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl)sulfinyl)-1H-benzimidazole.

-In order to improve the stability of the previously prepared novel antiulcer agent (I), 1-substituted benzimidazole derivatives are prepared, but they are less potent. However solvation of (I) by EtOH or H2O afford more stable compounds with antiulcer activities similar to that of the parent compound. -(

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ChemInform Abstract: Synthesis of Stable Solvates of Monosodium 2-((R*s,9S*)-(4-Methoxy-6,7, 8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl)sulfinyl)-1H-benzimidazole.

✦ Synopsis

Synthesis of Stable

ChemInform Abstract: Synthesis of Stable Solvates of Monosodium 2-((Rs,9S)-(4-Methoxy-6,7, 8,9-tetrahydro-5H-cyclohepta(b)pyridin-9-yl)sulfinyl)-1H-benzimidazole.