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4861780 4(3H)-quinazolinone derivatives and pharmaceutical compositions

✍ Scribed by Radmanesh, Farid; Caglayan, Ahmet Okay; Silhavy, Jennifer L.; Yilmaz, Cahide; Cantagrel, Vincent; Omar, Tarek; Rosti, Başak; Kaymakcalan, Hande; Gabriel, Stacey; Li, Mingfeng; Šestan, Nenad; Bilguvar, Kaya; Dobyns, William B.; Zaki, Maha S.; Gunel, Murat; Gleeson, Joseph G.

Book ID: 122050113
Publisher: Elsevier Science
Year: 1990
Tongue: English
Weight: 160 KB
Volume: 21
Category: Article
ISSN: 0306-3623
DOI: 10.1016/0306-3623(90)90860-O

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## Abstract magnified image A series of 2‐substituted‐4(3__H__)‐quinazolinones **13‐20** has been synthesized in good yields using the reaction of double lithiated 2‐methylquinazolinone‐4 with a variety of aromatic aldehydes. They have been easily transformed in high yields into the corresponding