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2,3-Dihydro-4(1H)-quinazolinone derivatives

✍ Scribed by Bonola, Giuseppe.; Sianesi, Enrico.


Book ID
121858241
Publisher
American Chemical Society
Year
1970
Tongue
English
Weight
371 KB
Volume
13
Category
Article
ISSN
0022-2623

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Discovery of a novel potent Na+/Ca2+ exc
✍ Hirohiko Hasegawa; Masami Muraoka; Kazuki Matsui; Atsuyuki Kojima πŸ“‚ Article πŸ“… 2003 πŸ› Elsevier Science 🌐 English βš– 211 KB

Design, synthesis and structure-activity relationships for 3,4-dihydro-2(1H)-quinazolinone derivatives with the inhibitory activities of the Na + /Ca 2+ exchanger are discussed. These studies based on lead compound 1a lead to the discovery of a structurally novel and highly potent inhibitor against