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Synthesis of Thiazino- and Thiazoloquinazolinones by Cyclization of S-(2-Propenyl) Derivatives of 2-Thioxo-2,3-dihydro-4(1H)-quinazolinone.

✍ Scribed by V. V. Orysyk; Yu. L. Zborovskii; V. I. Staninets; A. A. Dobosh; S. M. Khripak


Publisher
John Wiley and Sons
Year
2004
Weight
125 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract A novel one‐pot approach for the synthesis of aryl substituted quinazolin‐4(3__H__)‐ones and 2,3‐dihydro‐4(1__H__)‐quinazolinones has been reported based on the reductive desulfurization of 3‐aryl‐2‐thioxo‐4(3__H__)‐quinazolinones with nickel boride in dry methanol at ambient temperatur