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47. Allogeneic bone marrow transplantation in children with acute lymphoblastic leukemia in first and second complete remission conditioned with fractionated total body irradiation and etoposide or cyclophosphamide

✍ Scribed by J. Wachowiak; J. Malicki; D. Boruczkowski; G. Stryczyńska; G. Kosicka; M. Leda; A. Pieczonka

Publisher
Wielkopolskie Centrum Onkologii
Year
2001
Tongue
Polish
Weight
218 KB
Volume
6
Category
Article
ISSN
1507-1367

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✦ Synopsis

at the end ot treatmenł. We have noted also 38 patients (15%) ot 254 patients, with deacresing hemoglobin level during treatment higher than 1 gid!.

Results: No impact on outcome ot treatment was observed in the group ot patients with low level ot Hgb betore irradiation. Inrease ot locoregional failure ot postoperative radiotherapy was noted in group of patients with Hgb level at the end of irradiation below 13 g/dl (p = 0,004) and also in group ot patients with decreasing of Hgb level during treatment (p = 0,038).

Conclusions: Low Hgb levels at the end of postoperative irradiation and decreasing during irradiation were associated with a statistically signiticant an increase in locoregional failure ot patients with advanced carcinoma of larynx.

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