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419 Granules in glial cells of patients with Alzheimer's disease are immunopositive for C-terminal sequences of β-amyloid protein

✍ Scribed by H. Akiyama; C. Schwab; H. Kondo; H. Mori; F. Kametani; K. Ikeda; Patrick L. McGeer


Book ID
117413988
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
136 KB
Volume
17
Category
Article
ISSN
0197-4580

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Diffuse amyloid beta-protein (Abeta) deposits with numerous glial cells containing C-terminal Abeta fragments occur in the cerebral cortex of patients with Alzheimer's disease. By using a panel of antibodies specific for various epitopes in the Abeta peptide, we have investigated the immunohistochem