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416 Inhibition of fatty acid synthase by amentoflavone suppresses HER2/neu (erbB2) oncogene expression in breast cancer cells

✍ Scribed by E. Chang; J. Lee; M. Lee; E. Cha; J. Sul; W. Byun


Book ID
119601427
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
45 KB
Volume
8
Category
Article
ISSN
1359-6349

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## Abstract We designed our experiments to evaluate whether fatty acid synthase (FAS), a lipogenic enzyme linked to tumor virulence in population studies of human cancer, is necessary for the malignant transformation induced by Her‐2/neu (erbB‐2) oncogene, which is overexpressed not only in invasiv