✍ Scribed by Matthew P. Boente; Andrew Berchuck; Regina S. Whitaker; A. Kalén; Feng-Ji Xu; Daniel L. Clarke-Pearson; Robert M. Bell; Robert C. Bast Jr.
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Different epitopes on the extracellular domain of the HER-2 receptor can serve as distinct targets for immunotoxins. To determine the optimal epitope target for immunotoxin therapy, 7 anti-HER-2 ricin A chain murine monoclonal immunotoxins, each reactive with different epitopes of HER-2 receptor, we
## Abstract Over‐expression of the c‐__erb__B‐2 (HER‐2/__neu__) gene product p185 occurs in 30% of breast and ovarian cancers. The p185 protein might serve as a target for serotherapy in that antibodies against different epitopes on the extracellular domain of p185 can inhibit growth of tumor cells
Ionizing radiation is the exogenous agent best proven to induce breast cancer. c-erbB2/neu amplification and overexpression are known to occur in breast cancer and are correlated with aggressive tumor growth and poor prognosis. We have developed simian virus 40-immortalized cell lines from normal hu