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4109 POSTER Update on MTHFR Pharmacogenetics and Methotrexate Toxicity in Childhood Acute Lymphoblastic Leukemia

✍ Scribed by Lopez-Lopez, E.; Martin-Guerrero, I.; Ballesteros, J.; Uriz, J.; Pifian, M.A.; Garcia-Miguel, P.; Navajas, A.; Garcia-Orad, A.

Book ID: 122800607
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 40 KB
Volume: 47
Category: Article
ISSN: 0959-8049
DOI: 10.1016/S0959-8049(11)71287-4

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## Abstract ## Background Tromboembolic and hemorrhagic complications are significant causes of death in patients with malignancy. These are well‐known with the use of certain drugs. This study was planned to investigate whether there was any effect of high‐dose methotrexate on the hemostatic syst