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4-Benzyl-5-ethyl-2-(2-furylcarbonylmethylsulfanyl)pyrimidin-6(1H)-one

✍ Scribed by Zhang, Sui-Shuan ;He, Yan-Ping ;Zheng, Yong-Tang ;Rao, Zhi-Kun ;Li, Cong

Publisher
International Union of Crystallography
Year
2007
Tongue
English
Weight
975 KB
Volume
63
Category
Article
ISSN
1600-5368

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✦ Synopsis

The title compound, C 19 H 18 N 2 O 3 S, shows favourable activity against HIV-1. The phenyl ring is twisted with respect to the pyrimidine ring by 61.56 (9) . Intermolecular N-HÁ Á ÁO and C-HÁ Á ÁO hydrogen bonding links the molecules into a supramolecular chain structure and stabilizes the crystal structure of the compound.

📜 SIMILAR VOLUMES

(–)-1-Benzyl-4-[1(S)-phenyl­ethyl­amino]
(–)-1-Benzyl-4-[1(S)-phenyl­ethyl­amino]-5,6-dihydro­pyridin-2(1H)-one
✍ Romero, Nancy ;Terán, Joel L. ;Gnecco, Dino ;Bernès, Sylvain 📂 Article 📅 2005 🏛 International Union of Crystallography 🌐 English ⚖ 269 KB

In the title molecule, C 20 H 22 N 2 O, the pyridine heterocycle has an envelope conformation. The crystal packing is stabilized by intermolecular N-HÁ Á ÁO hydrogen bonds, which link the molecules into chains along the [110] direction.

3-(4-Fluoro­benzyl)-2-thio­xo-3,4,5,6-te
3-(4-Fluoro­benzyl)-2-thio­xo-3,4,5,6-tetra­hydro­pyrimidin-4(1H)-one
✍ Yao, Chang-Sheng ;Song, Hai-Bin ;Zhu, You-Quan ;Gao, Ying ;Hu, Fang-Zhong ;Zou, 📂 Article 📅 2004 🏛 International Union of Crystallography 🌐 English ⚖ 234 KB

The tetrahydropyrimidine ring of the title molecule, C 11 H 11 FN 2 OS, adopts a half-chair conformation. In the crystal structure, the molecules are linked to form centrosymmetric hydrogen-bonded dimers.