In the structure of the title compound, C 21 H 17 FN 4 O 2 S 2 , the fused thiazolopyrimidine ring system is nearly planar. The morpholine ring adopts a chair conformation. The crystal structure is stabilized by C-HÁ Á ÁO hydrogen bonds and weak stacking interactions.
5-Benzylamino-6-phenyl-2-propylsulfanylthiazolo[5,4-d]pyrimidin-7(6H)-one
✍ Scribed by Huang, Nian-Yu ;Yuan, Ju-Zhen ;Xu, Rui-Jun ;Ding, Ming-Wu ;He, Hong-Wu
- Publisher
- International Union of Crystallography
- Year
- 2005
- Tongue
- English
- Weight
- 209 KB
- Volume
- 62
- Category
- Article
- ISSN
- 1600-5368
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📜 SIMILAR VOLUMES
In the title compound, C 19 H 19 N 3 O, the five-membered imidazolone ring is essentially planar. Intermolecular N-HÁ Á ÁO hydrogen bonds form an infinite chain. The C-N and C-C bond lengths indicate electron delocalization.
The title compound, C 18 H 18 ClN 7 OS, the mean plane of the triazolopyrimidine system makes dihedral angles of 77.54 (13) and 80.15 (13) , respectively, with the attached phenyl and 2chlorothiazole rings. The crystal packing is stabilized by intermolecular N-HÁ Á ÁN hydrogen bonds and weakstacking
The title compound, C 19 H 18 N 2 O 3 S, shows favourable activity against HIV-1. The phenyl ring is twisted with respect to the pyrimidine ring by 61.56 (9) . Intermolecular N-HÁ Á ÁO and C-HÁ Á ÁO hydrogen bonding links the molecules into a supramolecular chain structure and stabilizes the crystal