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4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium chloride: an efficient condensing agent leading to the formation of amides and esters

✍ Scribed by Munetaka Kunishima; Chiho Kawachi; Jun Monta; Keiji Terao; Fumiaki Iwasaki; Shohei Tani

Book ID
108379479
Publisher
Elsevier Science
Year
1999
Tongue
French
Weight
968 KB
Volume
55
Category
Article
ISSN
0040-4020

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ChemInform Abstract: 4-(4,6-Dimethoxy-1,
ChemInform Abstract: 4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholinium Chloride: An Efficient Condensing Agent Leading to the Formation of Amides and Esters.
✍ Munetaka Kunishima; Chiho Kawachi; Jun Morita; Keiji Terao; Fumiaki Iwasaki; Sho πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 37 KB πŸ‘ 1 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Synthesis of sterically-hindered peptido
Synthesis of sterically-hindered peptidomimetics using 4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methyl-morpholinium chloride
✍ Wen-Chung Shieh; Zhuoliang Chen; Song Xue; Joe McKenna; Run-Ming Wang; Kapa Pras πŸ“‚ Article πŸ“… 2008 πŸ› Elsevier Science 🌐 French βš– 181 KB

Our study demonstrated that 4-(4,6-dimethoxy-1,3,5-triazine-2-yl)-4-methyl-morpholinium chloride (DMTMM) is a versatile coupling reagent for the synthesis of sterically-hindered peptidomimetics. It is superior to HBTU/HOBt and CDMT in controlling racemization and N-arylation, respectively.