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4-(2-Chloropropionyl)phenylacetoxy-polyethylene glycol: a new photolabile support for liquid phase peptide synthesis

✍ Scribed by Foe S. Tjoeng; George A. Heavner

Book ID: 104219632
Publisher: Elsevier Science
Year: 1982
Tongue: French
Weight: 211 KB
Volume: 23
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)85622-1

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✦ Synopsis

The synthesis of a photolabile 4-(Z-Chloropropionyl)phenylacetoxy-polyethylene glycol support and its application in liquid phase peptide synthesis is described. A protected pentapeptide is prepared and removed quantitatively from the support by irradiation at 350 nm.

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