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Liquid-phase method for peptide synthesis utilizing photolytic cleavage from a new o-nitrobenzoyl polyethylene glycol support

โœ Scribed by F-S. Tjoeng; W. Staines; S. St-Pierre; R.S. Hodges

Book ID
113125374
Publisher
Elsevier Science
Year
1977
Weight
477 KB
Volume
490
Category
Article
ISSN
0005-2795

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4-(2-Chloropropionyl)phenylacetoxy-polye
4-(2-Chloropropionyl)phenylacetoxy-polyethylene glycol: a new photolabile support for liquid phase peptide synthesis
โœ Foe S. Tjoeng; George A. Heavner ๐Ÿ“‚ Article ๐Ÿ“… 1982 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 211 KB

The synthesis of a photolabile 4-(Z-Chloropropionyl)phenylacetoxy-polyethylene glycol support and its application in liquid phase peptide synthesis is described. A protected pentapeptide is prepared and removed quantitatively from the support by irradiation at 350 nm.