## Abstract As a part of systematic investigation on synthesis and biological activities, some new derivatives of 2‐ethyl‐3‐(substituted benzothiazole‐2′‐yl)–[3__H__]‐quinazolin‐4‐ones **3** have been synthesized, and the structures of the compounds were confirmed by elemental analysis and spectral
3H-Quinazolin-4-ones as a New Calcilytic Template for the Potential Treatment of Osteoporosis.
✍ Scribed by Irina Shcherbakova; Manuel F. Balandrin; John Fox; Anjan Ghatak; William L. Heaton; Rebecca L. Conklin
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 17 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A new series of 2,3‐disubstituted quinazolin‐4(3__H__)‐one derivatives was synthesized by nucleophilic attack at C(2) of the corresponding key starting material 2‐propyl‐4__H__‐3,1‐benzoxazin‐4‐one (__Scheme 2__). The reaction proceeded __via__ amidinium salt formation (__Scheme 3__) ra
## Abstract magnified image A series of novel 4‐(4‐ethylphenyl)‐1‐substituted‐4__H__‐[1,2,4]triazolo[4,3‐__a__]quinazolin‐5‐ones were synthesized by the cyclization of 2‐hydrazino intermediate with various electrophile. The starting material 2‐hydrazino compound was synthesized from 2‐ethyl anilin