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Design and synthesis of new derivatives of 3H-quinazolin-4-one as potential anticonvulsant agents

✍ Scribed by Uma Kabra; Chandrabhan Chopde; Sudhir Wadodkar

Publisher
Journal of Heterocyclic Chemistry
Year
2011
Tongue
English
Weight
106 KB
Volume
48
Category
Article
ISSN
0022-152X

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✦ Synopsis

Abstract

As a part of systematic investigation on synthesis and biological activities, some new derivatives of 2‐ethyl‐3‐(substituted benzothiazole‐2′‐yl)–[3__H__]‐quinazolin‐4‐ones 3 have been synthesized, and the structures of the compounds were confirmed by elemental analysis and spectral data. The newly synthesized derivatives are then screened for anticonvulsant activity by maximal electroshock method. J. Heterocyclic Chem., (2011).

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