A novel series of CCR5 antagonists has been identified, utilizing the lead, nifeviroc, which were further modified based on bioisosteric principles. Lead optimization was pursued by balancing potential toxicity and potency. Potent analogues with low toxic properties were successfully developed by fo
✦ LIBER ✦
3D-QSAR studies of substituted 1-(3, 3-diphenylpropyl)-piperidinyl amides and ureas as CCR5 receptor antagonists
✍ Scribed by Yogesh D. Aher; Avantika Agrawal; Prasad V. Bharatam; Prabha Garg
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- English
- Weight
- 355 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1610-2940
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## Abstract For Abstract see ChemInform Abstract in Full Text.