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ChemInform Abstract: Synthesis and Biological Evaluation of 1-Cyclohexyl Substituted 3-Aminopyrrolidine Derivatives as CC Chemokine Receptor 2 (CCR2) Antagonists.

✍ Scribed by Jee Woong Lim; et al. et al.

Publisher: John Wiley and Sons
Year: 2010
Weight: 24 KB
Volume: 41
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201046101

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✦ Synopsis

Abstract

The 1‐cyclohexyl substituted 3‐aminopyrrolidine derivatives having a morpholine or thiomorpholine at the C‐4 position of the cyclohexyl group (II) are found to be good CCR2 antagonists.

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