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ChemInform Abstract: Asymmetric Synthesis and Biological Evaluation of N-Cyclohexyl-4- [1-(2,4-dichlorophenyl)-1-(p-tolyl)methyl]piperazine-1-carboxamide as hCB1 Receptor Antagonists.

✍ Scribed by Linghuan Gao; Min Li; Tao Meng; Hongli Peng; Xin Xie; Yongliang Zhang; Yu Jin; Xin Wang; Libo Zou; Jingkang Shen

Publisher: John Wiley and Sons
Year: 2012
Weight: 38 KB
Volume: 43
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.201211153

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✦ Synopsis

Abstract

Two enantiomers of the most potent racemic compounds in a series of recently discovered benzhydrylpiperazines are prepared using the Davis‐Ellmann‐type sulfonamide chemistry.

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