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Structural, conformational, biochemical, and pharmacological study of some amides derived from 3,7-dimethyl-3,7-diazabicyclo [3.3.1] nonan-9-amine as potential 5-HT3 receptor antagonists

✍ Scribed by M.J. Fernández; R.M. Huertas; E. Gálvez; A. Orjales; A. Berisa; L. Labeaga; A.G. Garcia; G. Uceda; J. Server-Carrió; M. Martinez-Ripoll


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
551 KB
Volume
372
Category
Article
ISSN
0022-2860

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Synthesis, structural, conformational an
✍ I. Iriepa; B. Gil-Alberdi; E. Galvez; J. Sanz-Aparicio; I. Fonseca; A. Orjales; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 2 views

A series of esters derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9a-ol (1) was synthesized and studied by 1 H and 13 C NMR spectroscopy, and the crystal structure of 3-methyl-2,4-diphenyl-9a-(3,5dimethylbenzoyloxy)-3-azabicyclo[3.3.1]nonane (2) was determined by x-ray diffraction. The