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Synthesis and structural, conformational, biochemical, and pharmacological study of new compounds derived from tropane-3-spiro4′(5′)-imidazoline as potential 5-HT3 receptor antagonists

✍ Scribed by B. A. Whelan; I. Iriepa; E. Galvez; A. Orjales; A. Berisa; L. Labeaga; A. G. Garcia; G. Uceda; J. Sanz-Aparicio; I. Fonseca

Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
660 KB
Volume
84
Category
Article
ISSN
0022-3549

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Synthesis, structural, conformational and pharmacological study of esters derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9α-ol as potential analgesics
✍ I. Iriepa; B. Gil-Alberdi; E. Galvez; J. Sanz-Aparicio; I. Fonseca; A. Orjales; 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB 👁 2 views

A series of esters derived from 3-methyl-2,4-diphenyl-3-azabicyclo[3.3.1]nonan-9a-ol (1) was synthesized and studied by 1 H and 13 C NMR spectroscopy, and the crystal structure of 3-methyl-2,4-diphenyl-9a-(3,5dimethylbenzoyloxy)-3-azabicyclo[3.3.1]nonane (2) was determined by x-ray diffraction. The