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394 Cyclin D1 gene amplification in human laryngeal squamous cell carcinomas: An independent prognostic factor

โœ Scribed by G. Almadori; A. Bellacosa; G. Cadoni; S. Cavallo; G. Ferrandina; J. Galli; G. Neri; G. Scambia

Book ID
116167148
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
160 KB
Volume
31
Category
Article
ISSN
0959-8049

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To evaluate the prognostic significance of cyclin D1 protein/gene expressions in human head-and-neck squamous-cell carcinoma (HNSCC), we examined amplification of the cyclin-D1 gene (CCND1) by the differential PCR method and over-expression of cyclin-D1 protein by immunohistochemistry in 45 paraffin