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Prognostic significance of cyclin D1 amplification and overexpression in oral squamous cell carcinomas

✍ Scribed by Ryozo Miyamoto; Narikazu Uzawa; Shunya Nagaoka; Yasushi Hirata; Teruo Amagasa

Book ID
114394004
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
242 KB
Volume
39
Category
Article
ISSN
1368-8375

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## Background: Abnormalities of chromosome band 11q13 are frequent in squamous cell carcinoma of the head and neck (scchn). the oncogene ccnd1 is located at 11q13 and encodes cyclin d1, a cell cycle-regulating protein. the authors investigated the clinical relevance and associations between amplifi