𝔖 Bobbio Scriptorium
✦   LIBER   ✦

345 EGF receptor studies using monoclonal antibodies

✍ Scribed by Mary Gregoriou; A.R. Rees

Book ID
116003797
Publisher
Elsevier Science
Year
1983
Tongue
English
Weight
142 KB
Volume
19
Category
Article
ISSN
0022-4731

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Development of ABX-EGF, a fully human an
Development of ABX-EGF, a fully human anti-EGF receptor monoclonal antibody, for cancer therapy
✍ Xiao-Dong Yang; Xiao-Chi Jia; Jose R.F. Corvalan; Ping Wang; C.Geoffrey Davis πŸ“‚ Article πŸ“… 2001 πŸ› Elsevier Science 🌐 English βš– 187 KB

Overexpression of epidermal growth factor receptor (EGFr) has been demonstrated on many human tumors, and the increase in receptor expression levels has been linked with a poor clinical prognosis. Blocking the interaction of EGFr and the growth factors could lead to the arrest of tumor growth and po

Specific targeting of a mutant, activate
Specific targeting of a mutant, activated egf receptor found in glioblastoma using a monoclonal antibody
✍ David Hills; Gail Rowlinson-Busza; William J. Gullick πŸ“‚ Article πŸ“… 1995 πŸ› John Wiley and Sons 🌐 French βš– 942 KB

## Abstract A truncated epidermal growth factor receptor (EGFR) expressed from a rearranged and amplified EGFR gene is present at high frequency in gliomas. In this work we show that when this receptor is expressed in NIH3T3 fibroblasts it is partially activated and confers tumorigenicity to this c

Interspecies scaling of the monoclonal a
Interspecies scaling of the monoclonal anti-EGF receptor ior EGF/r3 antibody disposition using allometric paradigm: is it really suitable?
✍ Jorge DucongΓ©; Eduardo FernΓ‘ndez-SΓ‘nchez; Daniel Alvarez πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 139 KB

## Abstract The pharmacokinetic regularity of the murine monoclonal antibody ior EGF/r3 across mammals was studied using allometry. The allometric relationship between the volume of distribution and body weight (__W__) across mammalian species was characterized by the power equation __V__~d~=218.8