Heterocyclic aldehydes such as 2-thiophenecarbaldehyde (1) condense with 3-aroylpropionic acids 2 or their sodium salts to give the enol lactones 3a-d of 3-aroyl-2-(2-thienylmethy-1ene)propionic acids. Isomerization of 3 ad leads to the corresponding 4-arylbenzo[b]thiophene-6-carboxylic acids 4a-d.
✦ LIBER ✦
323. β-Aroyl-α-arylmethylenepropionic acids. Part II. The synthesis and the mechanism of isomerisation of their enol lactones
✍ Scribed by El-Assal, Lanson S. ;Shehab, Awatef H.
- Book ID
- 121395264
- Publisher
- The Royal Society of Chemistry
- Year
- 1961
- Weight
- 470 KB
- Volume
- 0
- Category
- Article
- ISSN
- 0368-1769
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## Abstract __Zusammenfassung__. Im Rahmen der vorliegenden Mitteilung berichten wir über den partial‐synthetischen Aufbau von 3‐Oxo‐17 β‐acetoxy‐14α‐methyl‐Δ^4^‐8α, 9β, 10α, 13α‐östren (**12**), dessen Struktur anschliessend mittels dreidimensionaler Röntgenanalyse [2] sichergestellt worden ist. A